In the final scene of Casino Royale, Bond begins his journey to discovering the man responsible for Vesper’s betrayal and death, and subsequent movies follow him down the rabbit hole of exposing the evil organization Spectre and its leader, Ernst Blofeld (Christoph Waltz). At their behest, she worked to entrap Bond but later sacrificed her life in order to save his. That film ends with the revelation that Bond’s first true love, Vesper, was being blackmailed by a villainous figure.
That refusal to establish Bond film continuity changed in a big way with Casino Royale (2006), the first to star Daniel Craig in its title role.